I tried create a best workflow for me.
I start using a image reference and modifier skin for get a basemesh.
Then i sculpt until get a nice shape and a good sketch.
With a nice shape i start a retopologize for a get good loops and a clean topology.
In the next step i mark the seams and starts a paint the uvs and set the materials.
After paint the uvs, i setup the lights and camera position.
And finally, after some tests, i adjust the render settings in the cycles.
Blender 2.72 + Cycles
Concept by Piper Thibodeau
http://cryptid-creations.deviantart.com/gallery/